Oh man, I am VERY happy to see that RE 5 was generally reviled by other fans. The game is pretty to look at and all...but otherwise is almost unbearable otherwise. The horror element was completely gone from that game, and they really just took things too far with the story, and just took things too a new level of ridiculousness. I was vastly disappointed with the game after waiting over 3 years for it drop. (I was happy to see the Lickers return though...definitely geeked out about that for a minute).
BIOHAZARD 2 is my favorite in the series, for reasons that pretty much go without saying. I love all of the classic games though, with the exception of the side story/shooters that didn't interest me much. The Wii "rail-gun" shooters are an improvement on those earlier games, but like most of you, I'm DYING for a return to form for this series. Things NEED to be scary again. I enjoyed Zero, and the remake of the original game on the GC, but like bananaoil, felt Zero it to be unnecessary. NEMESIS felt like an extension of 2, while CODE VERONICA always felt like the "real" sequel to the second game. BIOHAZARD 4, I felt, was fantastic, and is my favorite in the series since CV. I feel it deserved all the praise that it got.
Anyways, I look forward to seeing what happens with the series, since it sounds like it's going to be a return to basics. I haven't been following things as closely, but is the next game going to be a "reboot" story wise, or just a reboot in terms of the actual game play and atmosphere (Less emphasis on action, more on horror)? I'd hate to see all of the characters we've grown to love disappear. It's been such a long journey, I would just hate to see it end so abruptly in favor of a new set of characters and situations.