Best known for her role of Yuki Ichinose in Godzilla 2000: Millennium (1999) and Maki Origuchi in Library Wars (2013), Naomi Nishida began her career as a model for commercials and magazines before starting her profession as an actress in daytime television. Her first feature film role was in the 1995 Alpine production Ice Blue. In the following years, Nishida landed two separate roles in the 2nd and 3rd entries in the successful Haunted School series before being awarded with a "Japan Academy Award for Newcomers" for her role in My Secret Cache (1997), a role which also netted her a "Special Jury Award" at the Hawaii International Film Festival. In the wake of her critical acclaim, Nishida landed the role of the lead female protagonist in the Millennium revival of the Godzilla series: Godzilla 2000: Millennium (1999).

In later years, Nishida would go on to star in the 2003 TV series Water Boys, which is based on the Toho film of the same name: Water Boys (2001). In 2005, Nishida revealed she had gotten married while two years later announced her pregnancy. She gave birth on April 6th, 2008, while making the announcement that she would not stop acting, and continues to be active in both television and film.